@article{261,
  keywords = {Complex systems, Cybersecurity, Defense, Immunology},
  author = {Edward Schrom and Ann Kinzig and Stephanie Forrest and Andrea Graham and Simon Levin and Carl Bergstrom and Carlos Castillo-Chavez and James Collins and Rob de Boer and Adam Doup{\'e} and Roya Ensafi and Stuart Feldman and Bryan Grenfell and Alex Halderman and Silvie Huijben and Carlo Maley and Melanie Moses and Alan Perelson and Charles Perrings and Joshua Plotkin and Jennifer Rexford and Mohit Tiwari},
  title = {Challenges in cybersecurity: Lessons from biological defense systems.},
  abstract = {<p>Defending against novel, repeated, or unpredictable attacks, while avoiding attacks on the {\textquoteright}self{\textquoteright}, are the central problems of both mammalian immune systems and computer systems. Both systems have been studied in great detail, but with little exchange of information across the different disciplines. Here, we present a conceptual framework for structured comparisons across the fields of biological immunity and cybersecurity, by framing the context of defense, considering different (combinations of) defensive strategies, and evaluating defensive performance. Throughout this paper, we pose open questions for further exploration. We hope to spark the interdisciplinary discovery of general principles of optimal defense, which can be understood and applied in biological immunity, cybersecurity, and other defensive realms.</p>},
  year = {2023},
  journal = {Mathematical biosciences},
  volume = {362},
  pages = {109024},
  month = {08/2023},
  issn = {1879-3134},
  doi = {10.1016/j.mbs.2023.109024},
  language = {eng},
}